Charlotte is best known for her play My Mother Said I Never Should, now translated into 23 languages and studied in schools, and named by the National Theatre as one of The Significant plays of the Twentieth Century. The premiere of this play was directed by the Palace's Artistic Director Brigid Larmour at Contact Theatre, Manchester in 1987. This partnership continued with The Ringing Singing Tree which premiered in 1991.

Charlotte and Brigid re-mounted My Mother Said I Never Should on the Watford stage in 2010.

In February 2012, Watford Palace Theatre produced the world premiere of Charlotte's new play Our Father, to critical acclaim. Directed by Brigid Larmour, Our Father was commended as being a ‘highly timely new play’ (Daily Telegraph), described by The Times as ‘a coup for Brigid Larmour, Artistic Director of Watford Palace Theatre’ and ‘a rich and unusual evening’ as well as ‘hugely ambitious’ (The Guardian)

Charlotte has written for radio, television and film and won the George Devine Award, Manchester Evening News Best New Play Award, a Time Out Award and was nominated for an Olivier Award as Most Promising Newcomer. She also reviews Arts for BBC Front Row and is writing a book about travelling in Georgia, East Europe.